Minimus is one of several assembly pipelines included in the AMOS software package. It is designed specifically for small data-sets, such as the set of reads covering a specific gene. Note that the code will work for larger assemblies (we have used it to assemble bacterial genomes), however, due to its stringency, the resulting assembly will be highly fragmented. For large and/or complex assemblies the execution of Minimus should be followed by additional processing steps, such as scaffolding. Minimus follows the Overlap-Layout-Consensus paradigm and consists of three main modules which share information through a central file bank: * hash-overlap - Computes the overlaps between the reads using a modified version of the Smith-Waterman local alignment algorithm * tigger - Uses the read overlaps to generate the layouts of reads representing individual contigs * make-consensus - Refines the layouts produced by the tigger to generate accurate multiple alignments within the reads Registration not required.